产品货号:
Z28258
中文名称:
TOP3B抗体
英文名称:
Anti-TOP3B Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TOP3B Antibody |
指标别名 | TOP3B;TOP3B1;DNA topoisomerase 3-beta-1;DNA topoisomerase III beta-1;DNA topoisomerase III beta |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ELISA |
基因名称 | TOP3B |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human TOP3B recombinant protein (Position:E128-R824). |
实际分子量 | 90~97KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | DNA topoisomerase 3-beta-1 is an enzyme that in humans is encoded by the TOP3B gene.This gene encodes a DNA topoisomerase,an enzyme that controls and alters the topologic states of DNA during transcription.This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another,thus relaxing the supercoils and altering the topology of DNA.The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination,cellular aging and maintenance of genome stability.Low expression of this gene may be related to higher survival rates in breast cancer patients.This gene has a pseudogene on chromosome 22.Alternate splicing results in multiple transcript variants.Additional alternatively spliced transcript variants of this gene have been described,but their full-length nature is not known. |
Uniprot ID | O95985 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
基因名全称 | DNA topoisomerase III beta |
蛋白名全称 | DNA topoisomerase 3-beta-1 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 ELISA 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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